Moébius Syndrome – Causes, Symptoms and Treatments!

Moébius Syndrome – Causes, Symptoms and Treatments that few know. In addition, Moébius Syndrome is a birth defect with no known cause, although it is associated with failed abortion attempts. The baby born with Moébius Syndrome has paralyzed facial nerves and is usually born with clubfoot and therefore needs corrective surgery.

People who have this Moébius Syndrome, in addition to not being able to make facial expressions, also have difficulty speaking and eating, but they do not have any brain deficiency , they are therefore very intelligent children, although they cannot demonstrate why they have difficulty expressing themselves. both through speech and facial expressions.

The best professionals to treat patients with Moébius Syndrome are neuropediatricians, speech therapists and psychologists, who, in addition to improving the patient’s quality of life, also help reintegrate the family.

Causes of Moébius Syndrome: Moébius  Syndrome is a medical condition that occurs as a result of injury to the nuclei of cranial nerves VI and VIII, and another that affects the cranial nerves located in the brain stem. However, currently, there are several theories that try to explain the etiological causes of this neurological damage. Some hypotheses suggest that  Moébius Syndrome is caused by interruption of cerebral  bloodduring embryonic pregnancy .

Ischemia or lack of oxygen supply can affect several areas of the brain , in this case the lower brain stem , where the cranial nerve nucleus. Likewise, the lack of blood supply can be due to environmental, mechanical or genetic factors.

Specifically, he has linked the occurrence of Moébius Syndrome in children whose mothers had eaten very high doses of misoprostol during pregnancy .

Misoprostol, a drug that acts on the uterus causing multiple contractions by reducing uterine and fetal blood flow. Thus, the mass use of this substance in clandestine abortion attempts was detected.

On the other hand, at the genetic level, most cases of Moébius Syndrome occur sporadically, in the absence of a family history. However, we have detected an inheritance line involving mutations in PLXND and REV3L.

In summary, although the causes of Moébius Syndrome are multiple (genetic, embryonic anomalies, teratogenic factors, etc.), in all cases there is a common extremity, poor development or destruction of cranial nerves VII and VI.

Symptoms of Moébius Syndrome:

• Lack of facial expression; Inability to smile.
• Feeding, swallowing and choking problems.
• Keep the head back to swallow.
• Eye sensitivity due to inability to pop.
• Engine lag due to upper body weakness.
• Absence of lateral eye movements .
• Absence of blinking.
• Strabismus (  crossed eyes ).
• Drooling.
• Taste high.
• Short or deformed tongue.
• Limited tongue movement.
• Submúbic futile palate.
• Dental problems.
• Hearing impairment.
• Articulation / speech disorders.
• Minor midline anomalies.
• Club feet.
• Hand Deformities / p.

Moébius Syndrome Treatments: Currently there is no method of intervention that guarantees a good margin of definite cure probability of Moébius Syndrome is known. Thus, treatments with patients with this pathology aim not to cure, but to mitigate the negative impact of symptoms and help for socialization and employment.

In this sense, an interdisciplinary work between different health professionals is necessary, such as neuropsychologists, neurologists, speech therapists, pediatricians and clinical and health psychologists, among others.

Psychotherapy can work through cognitive behavioral therapy to change limiting beliefs and improve patients’ self-esteem and train them in social skills, which together with the work of speech therapists help to break the isolation they often suffer. These people. You can also resort to surgery to correct malformations that are occurring, but always trying to correct bad posture habits from appearing in the future.