The 10 Causes of Acanthosis Nigricans
The Causes of Acanthosis Nigricans that we should not ignore. Additionally, Acanthosis Nigricans is a skin disorder characterized by darkening (hyperpigmentation) and thickening (hyperkeratosis) of the skin, mostly occurring in the skin folds in the armpit (armpit), groin, and back of the neck. Acanthosis Nigricans is not a skin disease per se, but a cutaneous sign of an underlying condition or disease. There are two important types of acanthosis: benign and malignant. Although classically described as a sign of internal malignancy, this is very rare. Benign types, sometimes described as “pseudoacanthosis nigricans”, are much more common. So, check out now The 10 Causes of Acanthosis Nigricans:
Causes of Acanthosis Nigricans: Acanthosis Nigricans can affect otherwise healthy people. There are many other possible causes of Acanthosis Nigricans , including:
- Genetic disorders, including Down syndrome
- Hormonal disorders such as diabetes, obesity
- Cancer, such as cancer of the digestive system, liver, kidney, bladder, or lymphoma
- Some medications, including hormones like human growth hormone or birth control pills
- Addison ‘s disease , a condition caused by a deficiency of adrenal gland hormones
- Disorders of the pituitary gland within the brain
- growth hormone therapy
- Hypothyroidism (low thyroid hormone levels caused by decreased thyroid gland activity)
- oral contraceptives
Most people with Acanthosis Nigricans have a higher insulin level than people of the same weight who do not have Acanthosis Nigricans . Eating too many of the wrong foods, especially starches and sugars, can increase insulin levels. Rarely, people with certain types of cancer can also develop Acanthosis Nigricans .
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Symptoms of Acanthosis Nigricans: Acanthosis Nigricans usually appears slowly and does not cause any symptoms other than skin changes. Eventually, dark, velvety skin with very visible marks and creases appears in the folds of the armpits, groin, and neck, and over the joints of the fingers and toes. Sometimes the lips, palms, soles of the feet or other areas are affected. These symptoms are more common in people with cancer.
Diagnosing Acanthosis Nigricans: Your doctor can usually diagnose Acanthosis Nigricans by looking at your skin. A skin biopsy may be necessary in rare cases. If there is no clear cause of Acanthosis Nigricans , your provider may order testing. These may include:
- Blood tests to check your blood sugar or insulin level
- Endoscopy
- X ray
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Acanthosis Nigricans Treatments: No treatment is necessary as Acanthosis Nigricans only causes a change in skin color. If the condition is affecting your appearance, using moisturizers containing ammonium lactate or hydroquinone can help soothe your skin. Certain lasers can also help the appearance. However, it is important to treat any underlying medical issues that could be causing these skin changes. When Acanthosis Nigricans is related to obesity , losing weight often improves the condition.