Tryptophan – what it is, benefits and side effects!

Purified tryptophan supplement is helpful in increasing the amount of serotonin in the brain while eating food does not even have the same effect. As such, many individuals have started using supplements to increase serotonin levels in the brain , which can result in better mood and better sleep patterns.

Tryptophan is not water soluble and also has remarkable heat resistance, making it a very durable compound. It also has a high degree of bioavailability. The amino acid has nootropic qualities in that it can alleviate symptoms of anxiety and depression , increase restful sleep, improve focus, and balance mood.

What is tryptophan?

Tryptophan is one of 23 proteinogenic (protein building) amino acids found in nature People need this nutrient as an important component for processing proteins and synthesizing serotonin .

It is worth remembering that it is one of the nine “essential” amino acids for humans. Essential amino acids are needed for different body functions; However, the body cannot produce these compounds internally. Essential amino acids, including tryptophan , must be obtained from food or dietary skin supplements .

What is tryptophan used for :

It is a precursor to a variety of hormones, neurotransmitters and other substances throughout the body. When this amino acid travels through the bloodstream, it supports the production or synthesis of different proteins. It is also a precursor to niacin , a B vitamin with several positive effects on the brain . It is still used to make serotonin , an important signaling substance.

Tryptophan is broken down in the liver into the compound 5-HTP and other metabolites. 5-HTP travels through the blood to the brain , crosses the blood-brain barrier and enters the brain . Once in the brain , 5-HTP is converted to serotonin .

Serotonin is known as the “happiness signaling substance” because the presence of serotonin in the brain is associated with positive feelings, including happiness, silence, and calm.

It is a precursor of serotonin ; is an important function in itself, but it also leads to a number of additional effects. Serotonin is supposed to help regulate things like appetite and mood. Some serotonins are also converted to melatonin , the hormone that regulates sleep/wake patterns (daytime rhythm).

What are the benefits of tryptophan?

One of the most important benefits of the amino acid is that it can help curb appetite and reduce symptoms of depression and anxiety . Studies have shown that low levels of tryptophan in the body can lead to anxiety and depression .

It has also been shown that the amino acid-derived serotonin has a limiting effect on appetite and may help reduce calorie intake and weight in obese individuals. The amino acid is still used to synthesize niacin, which is used in the treatment of carbohydrates and fats.

Tryptophan supplements can also encourage healthy sleep patterns. Furthermore, these benefits appear to be directly related to the release and synthesis of serotonin and melatonin . It  can still contain a fairly uniform serotonin throughout the day and help in producing the right level of melatonin at night.

This makes the amino acid different from other well-known serotonin precursors (and the tryptophan metabolite ), 5-HTP. When taken orally, 5-HTP is not subject to any rate limiting factors, meaning there is no control over how far serotonin levels can go.

Consequently, the amino acid’s effects may be less noticeable than 5-HTP, but with less risk of causing side effects. There are a number of medical conditions that tryptophan is able to improve. Also, the 2010 study showed that it can prevent the spread of a common liver disease called steatohepatitis.

Tryptophan Dosage :

As with most supplements, the dose you take will be determined by your specific purpose or condition. Also, for this reason, it is advisable to consult your physician or qualified medical professional before starting use.

Some sources indicate that the most common dose range is between 6 and 12 grams. Most adults (especially those looking to reduce symptoms of depression ) will take 3 or 4 tryptophan supplements distributed in daily administrations to ensure amino acid consistency.

Tryptophan side effects :

It is possible to overdo the overdose when tryptophan is taken in large amounts. In addition, it can lead to a number of possible side effects, including: agitation, confusion, fever, overactive reflexes, restlessness, chills, sweating, tremors, tingling, dizziness , dry mouth, or headache .

If any of these symptoms occur, it is recommended to discontinue use immediately and contact a physician. Also, after the side effects wear off, you can start using a lower dose.

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