Symptoms of Adult Still’s Disease that many are unaware of. Additionally, Adult Still’s Disease is a rare disease that causes high fevers , rashes, and joint pain . It can lead to prolonged (chronic) arthritis. The disease is still a severe version of juvenile idiopathic arthritis (JIA), which occurs in children.
Adults can have the same condition, although it is much less common. It is also called adult-onset disease (AOSD). Additionally, Adult Still’s Disease is a rare type of inflammatory arthritis that is similar to rheumatoid arthritis. It shares features of systemic-onset juvenile idiopathic arthritis, but begins in adulthood.
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Inflammation can affect some joints at first, but it can progress to include more joints over time. Some people may have just one bout of the disease followed by a lasting remission, while others may develop chronic arthritis.
Causes of Adult Still’s Disease: Less than 1 in 100,000 people develop Adult Still’s Disease each year. This affects women more often than men. The cause of the disease is still unknown. No risk factors for the disease were identified. So, check out now The 10 Symptoms of Adult Still’s Disease:
Symptoms of Adult Still’s Disease: Almost all people withadult-onset Adult Still’s Disease have fever , joint pain, sore throat, and a rash. But the type, pattern, and severity of symptoms vary from person to person and even from month to month for the same person. For example, symptoms may come and go. And at first, you may only have a few symptoms, and then you may have more. These are common symptoms of Adult Still’s Disease :
- A fever (102 degrees or higher) that comes on quickly once a day, usually in the afternoon or evening. For most people, these fevers resolve without treatment.
- Joint pain , heat, and swelling that affect a few joints at first — often knees and wrists — and then multiple joints . Morning joint stiffness usually lasts for several hours.
- A salmon pink rash that usually comes and goes with a fever and is usually not itchy. Flat spots or both flat and small, raised spots can appear on your torso, arms or legs, or face.
- Severe muscle pain, which may also have reflux with fever .
- A sore throat that can be severe, constant, and burning.
Other symptoms of Adult-onset Adult Still’s Disease may include:
- Abdominal pain and bloating
- Pain when breathing deeply
- Swollen glands (lymph nodes)
- unexplained weight loss
Contact your doctor if you have any of the symptoms of Adult -onset Adult Still’s Disease . If you’ve already been diagnosed and have had breathing problems, call your doctor right away. In addition to inflammation of the lung, liver, or heart, complications of Adult Still’s Disease can include chronic arthritis in multiple joints .
Diagnosis of Adult Still’s Disease: It can be difficult to diagnose Adult Still’s Disease . This is because Adult Still’s Disease has some similarities to other diseases such as Lyme disease, Crohn’s disease and certain infections. Before confirming your diagnosis, your doctor will need to rule out other problems.
A medical history and physical exam are often the first steps. You may need a variety of blood tests to check for inflammation, changes in blood cell counts, iron levels, and liver enzymes, for example. Imaging tests check for inflammation or enlargement of certain organs.
Adult Still’s Disease Tests and Tests: Adult Still’s Disease can only be diagnosed after many other diseases (such as infections and cancer) are ruled out. You may need many medical tests before making a final diagnosis. A physical exam may show fever , rash, and arthritis. The healthcare professional will use a stethoscope to listen for changes in the sound of the heart or lungs. The following blood tests may be helpful in diagnosing Adult Still’s Disease :
- Complete blood count (CBC) may show a high number of white blood cells and a low number of red blood cells.
- C-reactive protein (CRP), a measure of inflammation, will be higher than normal.
- ESR (sedimentation rate), a measure of inflammation, will be higher than normal.
- The ferritin level will be too high.
- The fibrinogen level will be high.
- Liver function tests will show elevated levels of AST and ALT.
- The rheumatoid and ANA test will be negative.
Other tests may be needed to check for inflammation of the joints , chest, liver, and spleen:
- abdominal ultrasound
- Computed tomography of the abdomen
- X-rays of the joints , chest, or stomach (abdomen)
Adult Still’s Disease Treatments: There is still no cure for Adult Still’s Disease . If you have been diagnosed, the goal is to control the symptoms and course of the disease. This can help prevent or lessen any complications. Early treatment for Adult Still’s Disease is aimed at controlling arthritis symptoms with non-steroidal anti-inflammatory drugs (NSAIDs).
NSAIDs include ibuprofen (Advil, Motrin), naproxen (Naprosyn, Aleve), and high-dose aspirin. These can start even before your diagnosis is confirmed. Analgesics, or pain medications, may also be prescribed. You may require these medications for some time. If so, your doctor will likely monitor your liver function and look for other side effects.
With a firm diagnosis of Adult-onset Adult Still’s Disease , you may need corticosteroids, such as prednisone, if your disease is severe or unresponsive to NSAIDs. Corticosteroids are used for systemic diseases that affect various parts of the body. Because of potential serious side effects, however, you can’t use them for long.
If you have a chronic case of Adult Still’s Disease , you may need medications to suppress your immune system and to control arthritis and other symptoms. You can take more than one medication at the same time, and you may need to take these for a long time. You take some medications by mouth and others by injection. These are examples of medications your doctor may prescribe:
- Anakinra (Kineret)
- Antitumor necrosis factor therapies: adalimumab (Humir), etanercept-szzs (Ereizi), etanercept (Enbrel), infliximab (Remicade), infliximab-dyyb (Inflectra), a biosimilar
- Azathioprine (Imuran)
- Cyclophosphamide (Cytoxan)
- Cyclosporine (Neural)
- Hydroxychloroquine (Plaquenil)
- Methotrexate (Rheumatrex)
- Sulfasalazine (Bluefidine)
If adult-onset Adult Still’s Disease affects your heart or lungs, your doctor may also need to prescribe medication to treat these problems.
Prevention of Adult Still’s Disease: There is no known prevention for Adult Still’s Disease .