Latest Research in the Treatment of Alzheimer’s Disease!

Latest Research in the Treatment of Alzheimer’s Disease. Furthermore, Alzheimer’s disease is a neurodegenerative disease that progressively progresses in patients. As a general rule, it affects neurons, the characteristic cells of the Nervous System.

In particular, neurons that are found in the cerebral cortex . The cortex or cerebral cortex  is a nervous tissue that is in the form of a layer above the cerebral hemispheres. It also changes other adjacent structures.

On the other hand, it is the subtype of dementia that appears most frequently in our society. In this way, 60% of dementias are caused by Alzheimer’s disease . However, experts estimate that there are a large number of clinical cases with this pathology undiagnosed.

Most common symptoms of Alzheimer’s disease:

Usually, the signs of this pathology are related to the activities of the Central Nervous System or the CNS. Therefore, a wide range of  cognitive and behavioral disturbance occurs. For example, among the most frequent we can highlight:

1. Mood changes unpredictably. In addition, the patient may show symptoms of depression , aggression, apathy, etc.;
2. Spatial and temporal disorientation (in relation to the time of year, month);
3. Difficulty performing daily activities, drawings, simple math operations;
4. Forgetting names and locating important objects (which leads to their loss).

In the most advanced stages, subjects present serious alterations associated with language. They don’t understand the meaning of words and can’t finish sentences. They also begin to develop problems with movement coordination and balance.

What are the causes of Alzheimer’s disease?

Currently, experts have determined that a set of biological and environmental factors can lead to the presence of this disease. A characteristic sign of the pathology is the appearance of senile plaques and tangles of neurofibrils.

The medical team was also able to identify several risk factors for this disease. It refers to the characteristics or habits of a patient that make him or her more prone to a pathology. In this case, smoking, advanced age and medical history with a history of medical history are the most decisive factors.

Treatments for Alzheimer’s disease:

As usual, the different treatments offered by the medical team need the consent of the patient. Likewise, different therapies seek to alleviate symptoms as much as possible. They will also seek to slow down the evolution of the disorder , stimulate cognitive functions and prevent new associated or derived pathologies. However, nowadays it is not known if there is a definitive cure for this disorder.

On the other hand, we can highlight two subtypes of therapy, depending on whether or not medication is used to help the patient. In this way we can find:

Non-pharmacological treatment:

Studies have shown that an adaptation of the environment in which the subject lives improves his psychological state. So you can easily identify the medium and remember moments that help you maintain your personality.

Recent research has shown that implanting a neurostimulator in the brain has very positive effects on subjects. As a rule, it is implanted in the early stages of the disease.

The device placed through a surgical intervention is able to mimic the functioning of the nervous system under normal conditions. However, the technique will not be fully developed for a decade, experts say.

Pharmacological treatment:

Psychotropics. In this category are included:

1. Antipsychotics;
2. Antidepressants;
3. Anxiolytics.

Other drugs like beta blockers, antiepileptic drugs, and:

1. NMDA (N-methyl-D-aspartate) receptor antagonists;
2. Acetylcholinesterase inhibitors (ACEI).

In this way, protection of the cholinergic system is ensured. This system is responsible for monitoring the information processed by the Nervous System. In any case, drug administration leads to exposure to side effects that should be known to families.