Imipramine – What is it for, how to use it and side effects
However, they do know that they interfere with the body’s ability to draw norepinephrine and serotonin back to nerve endings called synapses. This increases the concentrations of these chemicals in the brain. Originally manufactured by Sanofi Aventis, the Food and Drug Administration (FDA) first approved imipramine under the brand name Presamine in 1959. Presin was later discontinued.
How to Use Imipramine: Use imipramine as directed by your doctor. Check the label on the medication for exact dosing instructions.
- Imipramine comes with an extra patient information sheet called the Medication Guide . Read carefully. Read again each time you get refilled imipramine .
- Take imipramine by mouth with or without food.
- Taking imipramine at bedtime can help reduce side effects (eg, daytime sleepiness). Discuss this possibility with your doctor.
- It may take 1 to 3 weeks before you notice the effect of imipramine . Continue to use imipramine , even if you feel fine. Do not miss any doses.
- If you miss a dose of imipramine , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at the same time. If you take 1 serving daily at bedtime, do not take the missed dose the next morning.
- Ask your doctor any questions you may have about using imipramine .
Imipramine Side Effects: Get emergency medical help if you have any of these signs of an allergic reaction: hives; Difficult breathing; Swelling of the face, lips, tongue or throat. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety , panic attacks , trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically). ), more depressed, or have thoughts about suicide or harming yourself.
- Call your doctor right away if you have:
- Feeling that you might pass out;
- New or worsening chest pain, heartbeat or fluttering in your chest;
- Sudden numbness or weakness, problems with vision, speech or balance;
- Fever, sore throat;
- Easy bruising, unusual bleeding (nose, mouth, vagina or rectum), purple or red spots on your skin
- Confusion, hallucinations, unusual thoughts or behaviors;
- Painful or difficult urination;
- Seizure (seizures); or
- Jaundice (yellowing of the skin or eyes).
Other common side effects can include:
- Sensation of sensation, weakness, lack of coordination;
- Dry mouth, nausea, vomiting, constipation, diarrhea ;
- Blurred vision, ringing in your ears;
- Breast swelling (in men or women); or
- Decreased sexual desire, impotence or difficulty having an orgasm.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.