Gardner Syndrome – What is it, Causes and Treatments!
Gardner Syndrome – What it is, Causes and Treatments that we should all know. Furthermore, Gardner Syndrome is a rare genetic disorder. Usually, what starts to grow is benign or noncancerous.
It is classified as a subtype of familial adenomatous polyposis, which over time causes colon cancer . Gardner Syndrome can lead to growths in various areas of the body. Tumors are most commonly found in the colon, sometimes in large numbers.
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They tend to increase with age. In addition to polyps in the colon, growths can develop, including fibroids, desmoid tumors, and sebaceous cysts, which are fluid-filled growths under the skin.
Eye injuries can also occur to the retina in someone who has Gardner Syndrome . So, check now Gardner Syndrome – What is it, Causes and Treatments:
What Causes Gardner Syndrome: Gardner Syndrome is a genetic condition , meaning that it is inherited. The adenomatous polyposis coli (APC) gene mediates the production of the APC protein.
The APC protein regulates cell growth, preventing cells from dividing too quickly or in a disorderly fashion. People with Gardner Syndrome have a defect in the APC gene. This leads to abnormal tissue growth. What causes this gene to mutate has not been determined.
Main Symptoms of Gardner Syndrome: Common symptoms of this condition include:
- Colon growths:
- Development of extra teeth:
- Bone tumors in the skull and other bones:
- Cysts under the skin:
The main symptom of Gardner Syndrome is multiple growth in the colon. The growths are also known as polyps. Although the number of growths varies, they can be in the hundreds. In addition to growths in the colon, extra teeth can occur along with bone tumors in the skull.
Another common symptom of Gardner Syndrome is cyst, which can form under the skin in various parts of the body. Epithelial fibromas and cysts are common. People with Gardner Syndrome also have a much higher risk of colon cancer .
Treatment of Gardner Syndrome: Because people with Gardner Syndrome are at a higher risk of developing colon cancer , treatment is usually aimed at preventing this.
Medications such as an NSAID (sulindac) or a COX2 inhibitor (celecoxib) can be used to help limit the growth of colon polyps. Treatment also involves closely monitoring the polyps with endoscopy of the lower GI tract to ensure they do not become malignant (cancerous).
Once 20 or more polyps and/or multiple high-risk polyps are found, colon removal is recommended to prevent colon cancer . If there are dental abnormalities, treatment may be recommended to correct problems.
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As with all medical conditions, a healthy lifestyle with proper nutrition , exercise and stress reduction activities can help people cope with related physical and emotional issues.