Degos Disease – What is it, Symptoms and Treatments!

Degos Disease – What it is, Symptoms and Treatments of this condition. Also, Degos Disease is a rare disease that affects many organs at the same time. Degos Disease affects the skin , eyes , central nervous system, digestive , musculoskeletal, cardiovascular and respiratory systems, leading to death in a short time.

The main symptoms of Degos Disease are the appearance of some clear spots on the skin , mainly on the abdomen, which later spreads throughout the body. After some time the leg movements decrease causing imbalance, there is also a deviation of the gaze towards the nose and loss of control of the sphincter muscle.

The average life span of individuals with this disease is 1 to 3 years and to date there is no treatment for Degos Disease .

Causes of Degos Disease: The causes of Degos Disease have not yet been discovered; however, there are three hypotheses regarding its etiology. Are they:

  • Viral infection ;
  • Disturbance of immunity;
  • Changes in the blood clotting system .
  • Clinical manifestations include:

Cutaneous Lesions: they are usually multiple and appear predominantly on the trunk and upper limbs. They start as tiny red spots , about 2-5 cm in diameter. After a few days, these spots enlarge, with a white spot appearing right in the center of them. These heal and leave white scars.

Gastrointestinal Complications: they occur in 50% of cases of Degos Disease and are caused by the deficit of blood supply in the intestine , which can result in serious complications, such as, for example, intestinal perforation. Typically, an abrupt onset of abdominal pain or gastrointestinal bleeding is observed.

Nervous System Disorders: May result in stroke, headache, epilepsy , or non-specific neurological symptoms such as memory loss.

Symptoms of Degos Disease: The main symptoms of Degos Disease are the appearance of light spots on the abdomen, which spreads throughout the body. Then occur normally:

  • Progressive paresis in lower limbs;
  • Imbalance;
  • Hypoesthesia in the left hemibody;
  • Nasal deviation of gaze to the left and sphincter loss;
  • characteristic spots all over the body;
  • Bilateral palsy of the 3rd, 4th and 6th cranial nerves;
  • Left hypoesthesia, tetraparesis;
  • Hisarthria and dysmetria in the left upper limb;
  • Multiple subacute ischemic changes in the Brain;
  • Severe gastritis and duodenitis.

Diagnosis of Degos Disease: The diagnosis of Degos Disease is reached through histopathological examination of the skin , which shows necrosis of the dermis, with the absence or presence of a small amount of inflammatory cells.

Treatments for Degos Disease: To date, there is no known successful treatment for this disease. In some cases, antiplatelet drugs are used to reduce the number of lesions in patients with skin involvement. The survival of patients with this disease is around 2 to 3 years.

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